Preliminary reportFish oil prevents the adrenal activation elicited by mental stress in healthy men
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2022, Ageing Research ReviewsCitation Excerpt :A meta-analysis showed that subjects with depression had lower n-3 PUFA levels than control subjects; of the 2 most common n-3 PUFAs, EPA appears to be more effective than DHA in the treatment of depression (Martins, 2009). N-3 PUFAs are able to reduce plasma levels of cortisol, adrenaline and non-esterified fatty acids, leading to a reduction in mental stress (Delarue et al., 2003) and they can inhibit the NF-Kb pathway (Jolly et al., 2001), thus exerting protective effects against stress-induced inflammation (Bierhaus et al., 2003). DHA has a structural function, as it is present in the phospholipids of cerebral synaptosomes, in the retina and in the phospholipids of the intramembrane sodium channels, and it positively influences visual acuity and cognitive functions (Gil and Gil, 2015).
Health risk behaviours and allostatic load: A systematic review
2020, Neuroscience and Biobehavioral ReviewsCitation Excerpt :Additionally, AHA diet score was inversely associated with norepinephrine level in men (Mattei et al., 2013). This was supported by other studies, with low levels of norepinephrine and high energy carbohydrate diet consumption along with omega-3 supplementation especially during mental stress (Delarue et al., 2003; Young et al., 1992). They found that individuals on omega-3 supplementation blunted mental stress that almost abolished both epinephrine and cortisol secretion.